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1

The biosynthesis and regulation of bacterial prodiginines

Williamson, Neil R., Fineran, Peter C., Leeper, Finian J., Salmond, George P. C.

Journal:

Nature Reviews Microbiology

Year:

2006

Language:

english

File:

PDF, 1.26 MB

english, 2006

2

Stereoisomers of tetrahydrothiamin pyrophosphate, potent inhibitors of the pyruvate dehydrogenase multienzyme complex from Escherichia coli

Lowe, Peter N., Leeper, Finian J., Perham, Richard N.

Journal:

Year:

1983

Language:

english

File:

PDF, 993 KB

english, 1983

3

Biosynthesis of porphyrins and related macrocycles. Part 41. Fate of oxygen atoms as precorrin-2 carrying eight labelled carboxyl groups (13C18O2H) is enzymatically converted into cobyrinic acid

Vishwakarma, Ram A., Balachandran, Sarala, Alanine, Alex I. D., Stamford, N. Patrick J., Kiuchi, Fumiyuki, Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1993

Language:

english

File:

PDF, 833 KB

english, 1993

4

Stereochemical studies on porphyrin a: assignment of the absolute configuration of a model porphyrin by degradation

Battersby, Alan R., Cardwell, Kevin S., Leeper, Finian J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1986

Language:

english

File:

PDF, 2.34 MB

english, 1986

5

Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches

Kwasi Agyei-Owusu, Finian J. Leeper

Journal:

Year:

2009

Language:

english

File:

PDF, 791 KB

english, 2009

6

The spiro intermediate proposed for biosynthesis of the natural porphyrins: synthesis and properties of its macrocycle

Stark, W. Marshall, Baker, Mark G., Raithby, Paul R., Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1985

Language:

english

File:

PDF, 284 KB

english, 1985

7

Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate

Iqbal, Amjid, Sahraoui, El-Habib, Leeper, Finian J

Journal:

Beilstein Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 420 KB

english, 2014

8

Synthesis of and asymmetric induction by chiral bicyclic thiazolium salts

Roland L. Knight, Finian J. Leeper

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 212 KB

english, 1997

9

Synthesis of and asymmetric induction by chiral polycyclic thiazolium salts

A.Ulrich Gerhard, Finian J. Leeper

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 240 KB

english, 1997

10

Biosynthesis of the pigments of life: Structure and mode of action of a novel enzymatic cofactor

Peter R. Alefounder, Graham J. Hart, Andrew D. Miller, Uwe Beifuss, Chris Abell, Finian J. Leeper, Alan R. Battersby

Journal:

Bioorganic Chemistry

Year:

1989

Language:

english

File:

PDF, 467 KB

english, 1989

11

Synthesis of 3,4-Disubstituted Pyrroles. A Review

Leeper, Finian J., Kelly, James M.

Journal:

Organic Preparations and Procedures International

Year:

2013

Language:

english

File:

PDF, 2.38 MB

english, 2013

12

Biosynthesis of vitamin B12: mechanistic studies on the transfer of a methyl group from C-11 to C-12 and incorporation of 18O

Li, Yongfu, Alanine, Alex I. D., Vishwakarma, Ram A., Balachandran, Sarala, Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1994

Language:

english

File:

PDF, 290 KB

english, 1994

13

Rubrofusarin biosynthesis in Fusarium culmorum: incorporation of 13CH3 13CO2H and CD3 13CO2H into the polyketide naphthalene nucleus

Leeper, Finian J., Staunton, James

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1982

Language:

english

File:

PDF, 208 KB

english, 1982

14

Biosynthesis of vitamin B12: synthesis of (�)-[5-13C]faktor-1 ester: determination of the oxidation state of precorrin-1

Brunt, R. David, Leeper, Finian J., Grgurina, Ingeborg, Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1989

Language:

english

File:

PDF, 339 KB

english, 1989

15

Proof that the biosynthesis of vitamin B12 involves a reduction step in an anaerobic as well as an aerobic organism

Ichinose, Koji, Kodera, Masahito, Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1993

Language:

english

File:

PDF, 331 KB

english, 1993

16

Biomimetic syntheses of heptaketide metabolites: alternariol and a derivative of rubrofusarin

Leeper, Finian J., Staunton, James

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1978

Language:

english

File:

PDF, 140 KB

english, 1978

17

Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches

Cressina, Elena, Chen, Liuhong, Moulin, Michael, Leeper, Finian J., Abell, Chris, Smith, Alison G.

Journal:

Biochemical Society Transactions

Year:

2011

Language:

english

File:

PDF, 366 KB

english, 2011

18

ChemInform Abstract: Synthesis of 3,4-Disubstituted Pyrroles

Leeper, Finian J., Kelly, James M.

Journal:

Year:

2013

File:

PDF, 18 KB

2013

19

Stereocontrolled syntheses of polyhydroxy indolizidines, including 8a-epi-, 6,8a-diepi- and 1,6-diepi-castanospermine, starting from malic acid

Finian J. Leeper, Steven Howard

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 239 KB

english, 1995

20

Stereospecific nucleophilic ring-opening of a deuteriated cyclopropylcarbinol

Finian J. Leeper, Padma Padmanabhan

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 300 KB

english, 1989

21

Synthesis of 3,4-fused cycloalkanopyrroles by 1,3-dipolar cycloaddition

James M. Kelly, Finian J. Leeper

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 882 KB

english, 2012

22

Anticancer and immunosuppressive properties of bacterial prodiginines

Williamson, Neil R, Fineran, Peter C, Gristwood, Tamzin, Chawrai, Suresh R, Leeper, Finian J, Salmond, George PC

Journal:

Future Microbiology

Year:

2007

Language:

english

File:

PDF, 1.33 MB

english, 2007

23

Identification and characterisation of the gene cluster for the anti-MRSA antibiotic bottromycin: expanding the biosynthetic diversity of ribosomal peptides

Crone, William J. K., Leeper, Finian J., Truman, Andrew W.

Journal:

Chemical Science

Year:

2012

Language:

english

File:

PDF, 568 KB

english, 2012

24

Reactions of the carbanion from an orsellinate derivative with electrophiles

Carpenter, T. Adrian, Evans, Geoffrey E., Leeper, Finian J., Staunton, James, Wilkinson, Michael R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 1.43 MB

english, 1984

25

Syntheses relevant to vitamin B12 biosynthesis: the malate route to (?)-ring-B imide and synthesis of the 2,7,20-trimethylisobacteriochlorin

Whittingham, William G., Ellis, Martin K., Guerry, Philippe, Henderson, Graeme B., M�ller, Bernd, Taylor, David A., Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1989

Language:

english

File:

PDF, 362 KB

english, 1989

26

Biosynthesis of vitamin B12: the site of reduction of precorrin-6x

Weaver, George W., Leeper, Finian J., Battersby, Alan R., Blanche, Francis, Thibaut, Denis, Debussche, Laurent

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1991

Language:

english

File:

PDF, 364 KB

english, 1991

27

Synthesis of analogues of porphobilinogen

Leeper, Finian J., Rock, Martin, Appleton, Diana

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1996

Language:

english

File:

PDF, 1.52 MB

english, 1996

28

Modified substrates for tetrapyrrole biosynthesis: analogues of porphobilinogen showing unusual inhibition of porphobilinogen deaminase

Leeper, Finian J., Rock, Martin

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1992

Language:

english

File:

PDF, 315 KB

english, 1992

29

Biomimetic syntheses of polyketide aromatics from pyrylium salts

Griffin, David A., Leeper, Finian J., Staunton, James

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 1.10 MB

english, 1984

30

(E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent

Stöckmann, Henning, Neves, André A., Day, Henry A., Stairs, Shaun, Brindle, Kevin M., Leeper, Finian J.

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

31

A Fragment-Based Approach to Identifying Ligands for Riboswitches

Chen, Liuhong, Cressina, Elena, Leeper, Finian J., Smith, Alison G., Abell, Chris

Journal:

ACS Chemical Biology

Year:

2010

Language:

english

File:

PDF, 215 KB

english, 2010

32

Biosynthesis of porphyrins and related macrocycles. Part 47.1,2 Synthesis and chemistry of 2H-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis

Hawker, Craig J., Stark, W. Marshall, Spivey, Alan C., Raithby, Paul R., Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1998

Language:

english

File:

PDF, 362 KB

english, 1998

33

Synthetic studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins: the stereochemical probe

Cassidy, Mark A., Crockett, Nigel, Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1991

Language:

english

File:

PDF, 268 KB

english, 1991

34

Biosynthesis of porphyrins and related macrocycles. Part 45. Determination by a novel X-ray method of the absolute configuration of the spiro lactam which inhibits uroporphyrinogen III synthase (cosynthetase)

Spivey, Alan C., Capretta, Alfredo, Frampton, Christopher S., Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1996

Language:

english

File:

PDF, 1.91 MB

english, 1996

35

Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging

Neves, André A., Wainman, Yéléna A., Wright, Alan, Kettunen, Mikko I., Rodrigues, Tiago B., McGuire, Sarah, Hu, De-En, Bulat, Flaviu, Geninatti Crich, Simonetta, Stöckmann, Henning, Leeper, Finian J.,

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 5.09 MB

english, 2016

36

Sub-ångström-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate

Lüdtke, Stefan, Neumann, Piotr, Erixon, Karl M., Leeper, Finian, Kluger, Ronald, Ficner, Ralf, Tittmann, Kai

Journal:

Nature Chemistry

Year:

2013

Language:

english

File:

PDF, 1.89 MB

english, 2013

37

Synthesis of ?-1-homonojirimycin and ?-1-homomannojirimycin using the enzyme aldolase

Holt, Karen E., Leeper, Finian J., Handa, Sheetal

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1994

Language:

english

File:

PDF, 556 KB

english, 1994

38

Biosynthesis of vitamin B12: studies of the oxidative and lactone-forming steps by 18O-labelling

Alanine, Alex I. D., Li, Yongfu, Stamford, N. Patrick J., Leeper, Finian J., Blanche, Francis, Debussche, Laurent, Battersby, Alan R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1994

Language:

english

File:

PDF, 268 KB

english, 1994

39

Biosynthesis of the indolizidine alkaloid cyclizidine: incorporation of singly and doubly labelled precursors

Leeper, Finian J., Shaw, Susan E., Satish, Padma

Journal:

Canadian Journal of Chemistry

Year:

1994

Language:

english

File:

PDF, 662 KB

english, 1994

40

Rücktitelbild: Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging (Angew. Chem. 4/2016)

Neves, André A., Wainman, Yéléna A., Wright, Alan, Kettunen, Mikko I., Rodrigues, Tiago B., McGuire, Sarah, Hu, De-En, Bulat, Flaviu, Geninatti Crich, Simonetta, Stöckmann, Henning, Leeper, Finian J.,

Journal:

Angewandte Chemie

Year:

2016

File:

PDF, 2.56 MB

2016

41

Biosynthesis of porphyrins and related macrocycles, part 43. Isolation and characterization of intermediates of coenzyme B12 biosynthesis, a cobyrinic acid triamide, the a,c-diamide and their Co-(5′-deoxy-5′-adenosyl) derivatives, from Propionibacterium shermanii

Fumiyuki Kiuchi, Finian J Leeper, Alan R Battersby

Journal:

Chemistry & Biology

Year:

1995

Language:

english

File:

PDF, 709 KB

english, 1995

42

Biosynthesis of porphyrins and related macrocycles. Part 35. Discovery of a novel dipyrrolic cofactor essential for the catalytic action of hydroxymethylbilane synthase (porphobilinogen deaminase)

Hart, Graham J., Miller, Andrew D., Beifuss, Uwe, Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1990

Language:

english

File:

PDF, 1.95 MB

english, 1990

43

[Topics in Current Chemistry] Biosynthesis Volume 209 ||

Leeper, Finian J., Vederas, John C.

Year:

2000

Language:

english

File:

PDF, 3.76 MB

english, 2000

44

Biosynthesis of the polyketide antibiotic ICI139603 in Streptomyces longisporoflavus: assignment of the 13C n.m.r. spectrum by two-dimensional methods, and determination of the origin of the carbon atoms

Bulsing, J. Mark, Laue, Ernest D., Leeper, Finian J., Staunton, James, Davies, David H., Ritchie, Graham A. F., Davies, Alan, Davies, Alan B., Mabelis, Richard P.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1984

Language:

english

File:

PDF, 221 KB

english, 1984

45

Interaction of analogues of porphobilinogen with porphobilinogen deaminase

Leeper, Finian J., Rock, Martin

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1996

Language:

english

File:

PDF, 971 KB

english, 1996

46

Preparation of [4R-3H]NADH, [4R-3H]NADPH and the corresponding 4S-isomers all with substantial specific activities

Ichinose, Koji, Leeper, Finian J., Battersby, Alan R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1993

Language:

english

File:

PDF, 523 KB

english, 1993

47

Biosynthesis of porphyrins and related macrocycles. Part 30. Synthesis of the macrocycle of the spiro system proposed as an intermediate generated by cosynthetase

Stark, W. Marshall, Baker, Mark G., Leeper, Finian J., Raithby, Paul R., Battersby, Alan R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1988

Language:

english

File:

PDF, 2.15 MB

english, 1988

48

The structure of polivione, a polyketide co-metabolite of citromycetin in Penicillium frequentans

Demetriadou, Agathi K., Laue, Ernest D., Leeper, Finian J., Staunton, James

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1985

Language:

english

File:

PDF, 267 KB

english, 1985

49

ChemInform Abstract: Biosynthesis of Porphyrins and Related Macrocycles. Part 51. Proof that a Reductive Step Occurs During the Biosynthesis of Vitamin B12 by the Microaerophilic Organism, Propionibacterium shermanii.

Koji Ichinose, Masahito Kodera, Finian J. Leeper, Alan R. Battersby

Journal:

Year:

1999

File:

PDF, 27 KB

1999

50

Biosynthesis of the pigments of life: mechanistic studies on the conversion of porphobilinogen to uroporphyrinogen III

Battersby, Alan R., Leeper, Finian J.

Journal:

Chemical Reviews

Year:

1990

Language:

english

File:

PDF, 2.55 MB

english, 1990

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